|
HClust |
Input | |
Expression data | Input file in seltag format |
Fields select |
List of fields - List of expression fields (tissues) used to calculate correlation between gene expression profiles, namely field indices in data format of input file starting from 1 (column numeration is not depend on the Case Names option). Examples of input:
|
Genes for select |
List of genes - List of genes to calculate correlation, namely gene indices in data set of input file starting from 1 (column numeration is not depend on the Case Names option). Examples of input:
|
Output | |
Result | Name of output file |
Options | |
Type of distance | Three types of distance are possible with respect to correlation coefficient rij: 1-rij; 1-|rij|; 1+rij |
Type of correlation | Type of correlation coefficient. Three types of correlations are possible: Pearson's r, Spearman rank correlation and Kendall tau correlation. |
Clustering threshold value | The value of clustering threshold. |
Missing data treatment | Option to treat missing data. Several options are possible: Substitute by means (missing data are substituted by expression means in corresponding field); Case-wise deletion (correlations/distances are calculated by excluding cases that have missing data for any of the selected variables, all correlations are based on the same set of data); Pair-wise deletion (correlations/distances between each pair of profiles are calculated from all fields/samples having valid data for those two profiles). |